Before kickoff against the Chiefs, the team announced that Deebo Samuel was dealing with an illness, but that he'd start against the Chiefs on Oct. 20. Samuel, who signed a three-year extension worth $71.55 million in 2022, managed to play just a few snaps before exiting the game.

The Kansas City Chiefs continued a run of dominance over the San Francisco 49ers — while also keeping the NFL’s only unbeaten record intact. KC had three interceptions, including two from seldom-used rookies, while continuing to grind out efficiency on offense in a 28-18 road victory on Sunday afternoon at Levi’s Stadium.