Can DNA-nanoparticle motors get up to speed with motor proteins?
DNA-nanoparticle motors are exactly as they sound: tiny artificial motors that use the structures of DNA and RNA to propel motion by enzymatic RNA degradation. Essentially, chemical energy is converted into mechanical motion by biasing the Brownian motion.
The motion of motor proteins on biopolymers is important for diverse biological processes. Actin, microtubules, and nucleic acids can serve as one-dimensional tracks on which motor proteins move.
The new finding is published in Cell in an article titled, “ SMC motor proteins extrude DNA asymmetrically and can switch directions ,” and is key to understanding how these motors shape our genome ...
These latter movements are currently thought to be catalyzed by motor proteins that connect microtubules with opposite polarity and then "walk" toward the end of the microtubules. Mitosis ends ...
We even identified the 'gear lever', protein subunit NIPBL, in the cohesin SMC motor protein." To discover the reverse gear of SMC motors, the researchers used an advanced home-built microscope ...
Combining a premade SMN protein with a Spinraza-like drug (targets SMN2 gene) helped patient-derived motor neurons; potential ...
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