The Hughes Fire has spread over 5,054 acres after starting just before lunchtime in Los Angeles County's Castaic Lake area on Wednesday.

The blaze, being called the Chambers Fire, was first reported at around 6:10 p.m. near Chambers Street and Gilbert Street, according to the Cal Fire/Riverside County Fire Department. A woman who lost 64 pounds on a compounded form of the weight loss drug semaglutide,

As winds across the Southern California area are calmer than their peak and firefighters are making progress, the threat to the fire-weary region remains with Santa Ana winds expected to continue in the coming days.