The 49ers (6-9) could secure last place in the NFC West with a loss tonight, but that still won’t secure the NFC playoffs’ No ...

The Detroit Lions are missing several key players entering their Week 17 game against the San Francisco 49ers, but there is a ...

Kickoff between the San Francisco 49ers and Detroit Lions is just hours away. Ahead of their Week 18 matchup at Levi's ...

Detroit Lions and San Francisco 49ers meet on Monday Night Football in NFL Week 17. Find live updates, score summary, game ...

The Lions have already defeated the Vikings once this season at U.S. Bank Stadium. If Detroit wins again, they're in based on ...

The Lions will have linebacker Jalen Reeves-Maybin back for Monday night's game against the 49ers.Reeves-Maybin has been activated from injured reserve.

The Dallas Cowboys were one of the best teams at wheeling and dealing in the early 90’s, but the trend stopped. What happened ...

After building a 17-point halftime lead, the Lions were unable to finish the game and the San Francisco 49ers rallied to ...

The Los Angeles Rams (10-6) clinched the NFC West on Sunday night and are now slated to host a playoff game in the first week of the NFC Wild Card playoffs. The ...

Check out these five of the best anytime TD prop bets for this NFL matchup between the 49ers and Lions on MNF. Find key stats ...

Listing our expert Penn Live picks of the best prop bets and odds available for tonight's Monday Night Football NFC matchup ...

The Lions travel to Santa Clara to battle the 49ers on Monday Night Football. The 49ers-Lions game starts at 8:15 p.m. ET on ...