The Washington State cornerback swarmed to the ball from the upper portion of the field to lay a powerful hit on Cenacle. His ...

The San Francisco 49ers and fantasy football managers won't have star wide receiver Brandon Aiyuk at their disposal anytime soon following his knee injury.

San Francisco 49ers standout wide receiver Brandon Aiyuk tore his ACL and MCL in Sunday's loss to the Kansas City Chiefs and ...

Coach Kyle Shanahan said tests Monday confirmed the initial diagnosis Aiyuk tore his ACL and would need major reconstructive ...

KANSAS CITY — The Kansas City Chiefs just keep winning, even as the injuries continue to pile up.

NFL fans are upset with the officiating during the Kansas City Chiefs' 28-18 victory over the San Francisco 49ers. Late during the fourth quarter, with the 49ers on offense, there was a scrum between ...

And yet Kyle Shanahan treated it like he treats all games: He played not to lose. So the 49ers lost.

Already missing star running back Christian McCaffrey to Achilles tendinitis in both his calves, the team also lost star wideouts Deebo Samuel and Brandon Aiyuk during Sunday's 28-18 loss to the ...

One of the best runners in the NFL will be on display when Jordan Mason and the San Francisco 49ers host the Dallas Cowboys ...

Before kickoff against the Chiefs, the team announced that Deebo Samuel was dealing with an illness, but that he'd start ...

NFL on FOX' has been accused of stealing a video from a local reporter and not crediting them for it, while even cropping a ...

The strength of the San Francisco 49ers' offense the past few seasons has been the number of dynamic playmakers that makes it ...