Injuries always have a significant effect on the NFL season, but some teams are bearing the brunt of absences more than ...

It isn’t news that running back and reigning Offensive Player of the Year Christian McCaffrey is a key cog in the 49ers’ ...

At linebacker, Dee Winters had his best game of the season while Kyle Shanahan provided a rough timeline for Dre Greenlaw's ...

The Cowboys didn’t shuffle the roster at all over the bye, leaving just on-field adjustments against the 49ers as the last ...

Jauan Jennings, wide receiver for the San Francisco 49ers, suffered a significant injury during a game against the Seattle ...

The San Francisco 49ers’ worst suspicions were confirmed Monday when it was learned Brandon Aiyuk was lost for the season ...

And even though Bo Nix has work to do with his feet and has plenty of things he can improve, Payton knows he has a QB with ...

In his best game of the season, Brandon Aiyuk finished with 14.7 fantasy points -- eight receptions, 147 yards. That was in ...

The strength of the San Francisco 49ers’ offense the past few seasons has been the number of dynamic playmakers that makes it ...

The San Francisco 49ers and fantasy football managers won't have star wide receiver Brandon Aiyuk at their disposal anytime soon following his knee injury.

Following the significant losses of players due to injury and illness, including Brandon Aiyuk, San Francisco 49ers head ...

The first year of Aiyuk's $120 million four-year contract extension, which was marked by a long dispute with the 49ers, ...